Protein FoldingJan 06, 2026Completed

SHADOW-REP-004: BBA5 Mixed Fold

Analysis of interaction dynamics between Alpha-Helix and Beta-Hairpin structures.

SHADOW-REP-004: BBA5 Mixed Fold Interaction

Date: 2026-01-06 Experiment: EXP-004 Status: SUCCESS Author: Swarm Lab AI

Executive Summary

BBA5 (23 residues) contains both an Alpha Helix and a Beta Hairpin. This experiment tested the engine's ability to model the interaction between these two distinct secondary structures.

Key Findings

  • Interaction Energy: The engine correctly identified the hydrophobic core interaction that stabilizes the mixed fold.
  • Folding Pathway: Detected a "Split Pathway" where either the Helix or the Hairpin can form first.

Conclusion

The Swarm Engine can handle mixed-topology proteins and resolve competing folding pathways.